Blow-Fill-Seal machines are used a lot to make safe packages for liquids like medicines, drinks, and creams. They can make bottles, fill them, and seal them all in one go, so everything stays clean and safe. These machines are super important in industries like healthcare and food because they help keep things sterile.

The market for these machines was worth about $3.2 billion in 2023. Experts think it will grow to $7.1 billion by 2032 because more and more companies need this kind of packaging. The growth shows how much people trust these machines to keep their products safe and clean.

Rommelag

Year Founded: 1952

Main Products

• Blow-Fill-Seal (BFS) packaging systems and machines
• Aseptic filling solutions
• Containment systems for pharmaceuticals
• Bottelpack machines

Company Description

Rommelag is a company from Germany that came up with a cool way to pack liquids and creams called Blow-Fill-Seal (BFS) technology. They started making their first BFS machine, called the bottelpack, in 1962. Now, they have more than 2,000 workers and sell their machines to people in over 80 countries.

Their machines do three jobs in one. They make plastic bottles, fill them with the product, and seal them shut, all in just a few seconds. The process happens in super clean spaces so everything stays safe. These machines save time because you don’t need to wash or clean containers, and they always do the job just right.

The company has four parts: Engineering, CMO (where they make products for other companies), Flex, and Service. Their main offices are in Switzerland and Germany. They also have offices in China and the USA and work with partners in over 20 other countries.

Their machines are really useful for making medicine containers. These containers come in all kinds of shapes and sizes, and they’re made to be safe and easy to use. They can even be changed to match different needs.

Catalent

Year Founded: 2007

Main Products

• Drug delivery technologies and development services
  • Softgel solutions and Liqui-Gels® capsules
  • Zydis® fast-dissolve formulations
  • Biologics manufacturing
  • Gene therapy solutions
  • Clinical supply services

Company Description

Catalent is a company from New Jersey that started in 2007. They help make medicines for people all over the world. With over 14,000 workers, including many scientists, they work hard to make drugs safe and helpful.

They team up with big medicine companies to create new drugs. They have factories in 28 places around the world and make over 100 billion medicine pieces every year. That’s a lot of medicine helping lots of people!

In their big factory in Illinois, they use a special method called Blow-Fill-Seal, or BFS. This means they make the bottle, fill it with medicine, and seal it all at once. This keeps the medicine very safe and clean because it doesn’t touch the air much.

Catalent has grown by joining with other companies over the years. They make many kinds of medicines, like pills that dissolve quickly and special capsules. They even help with gene therapy, which is a new way to treat diseases.

They played a big part in making COVID-19 vaccines by working with companies like Pfizer and Moderna. With their help, new medicines can reach people faster.

Unither Pharmaceuticals

Year Founded:1993

Main Products

• Sterile single-dose medicines using Blow-Fill-Seal technology
• Eye drops
• Saline solutions
• Asthma medicines
• Stick-pack products
• Preservative-free multidose items

Company Description

Unither Pharmaceuticals makes special medicines in tiny, one-dose packages. They use a neat method called Blow-Fill-Seal that fills and seals the medicine all at once. This helps keep the medicine clean and safe.

They have factories in Europe, North America, South America, and Asia. Every year, they can make up to 5 billion doses of medicine. They grew bigger by adding new places in the United States, Brazil, and China.

Lots of important health agencies trust them, like the FDA in the United States and others in Europe, Brazil, and China. By 2023, they had over 2,200 people working in eight factories. They sold medicines worth 475 million euros that year.

Their special way of making medicines keeps them super clean. They use filters and special air showers to make sure everything is sterile. Because of this, many companies around the world ask them to make medicines for them.

Weiler Engineering

Year Founded: 1959

Main Products

• ASEP-TECH® Blow/Fill/Seal Packaging Machines
• Custom Aseptic Packaging Systems
• Automation Systems

Company Description

Weiler Engineering, Inc. makes special machines for medicines and healthcare products. They’ve got a big factory near Chicago’s O’Hare Airport.

Their amazing invention is the ASEP-TECH® Blow/Fill/Seal system. For over 50 years, they’ve been making this machine even better. It can make, fill, and seal bottles all at once!

These machines use clever technology to put just the right amount of liquid into each bottle. They keep everything super clean, so the medicines stay safe and germ-free.

With cool air filters and sterilization systems, they make sure no nasty germs sneak in. This helps them make things like eye drops and breathing medicines that people need.

Weiler Engineering has about 78 folks working hard to make sure medicines are made safely. Their machines help get important medicines to people everywhere.

Recipharm

Year Founded: 1995

Main Products

• Solid, liquid, semi-solid medicines
• Inhalers and devices
• Germ-free medicines (like eye drops and BFS)
• Medicines you can inject
• Eye care products

Company Description

Recipharm helps make medicine for other companies. They make new kinds of medicine and lots of it so people everywhere can get what they need. Over 5,000 people work for them in places like Sweden, India, and the US.

They use machines that keep the medicine super clean and safe. This is really important for things like eye drops and shots so no germs can get in.

They work with many companies to make the medicines they need. Recipharm has factories in lots of countries and keeps building more to help even more people.

They’re one of the biggest companies making medicine. They keep getting better by using new machines and teaming up with others to make sure everything they make is safe and good quality.

HealthStar

Year Founded: 1983

Main Products

• Blow-Fill-Seal (BFS) machinery and production lines
• Processing and packaging equipment
• Custom molds and tooling

Company Description

HealthStar makes machines that help companies put stuff like medicine into packages safely. Their Blow-Fill-Seal machines make and seal containers all in one step, so nothing gets dirty or unsafe. They also build special tools and molds to fit what each customer needs.

The company started in Braintree, Massachusetts, to give businesses affordable machines they could trust. They fix up older machines by taking them apart and putting in new parts, making them work better than before. Their machines are used to make medicine, food, and other important things.

HealthStar works with people everywhere in the world. They sell rebuilt machines and make custom designs to help with different projects. Their workers help customers from start to finish, including setting up the machines and making sure they work right.

Lots of businesses use HealthStar machines because they’re super clean and safe. Their machines are great for packing medicine, and big health groups like the FDA say they’re perfect for keeping everything sterile. HealthStar has been doing this for years and keeps finding new ways to help companies.

Pharmapack

Year Founded: 1997

Main Products

• Pharmaceutical Packaging Solutions
• Drug Delivery Systems
• Medical Devices
• Packaging Machinery

Company Description

Pharmapack started small as a place where companies could show their packaging machines. It became really big, with over 300 companies joining and visitors from 75 countries. Now, it’s one of the most important events for medicine packaging.

They use a cool process called Blow-Fill-Seal. This method makes medicine containers, fills them up, and seals them tight all at the same time. Everything happens in a super clean area to keep the medicine safe.

Their machines can handle lots of different things like liquids, gels, and even medicines that need special care. They make containers for one-time use or ones with handy features like twist tops. This way, the medicine stays fresh and lasts longer.

Pharmapack’s machines work fast and help companies save time while making sure everything is clean and safe. Businesses all over the world use them to keep their medicines ready for people who need them.

GEA Group

Year Founded: 1881

Main Products

• Aseptic blow molding machines with integrated filling systems
• Separation and flow technology equipment
• Food processing machinery
• Dairy farming equipment
• Heating and refrigeration systems

Company Description

GEA Group makes machines that help companies make food, drinks, and medicine. Their machines can create and fill bottles in one step, which keeps everything clean and safe. The company is based in Düsseldorf, Germany, and is known for its smart and reliable technology.

Their machines use a special cleaning process with hydrogen peroxide to clean bottles and caps before filling them. This makes sure things like milk or juice stay fresh and free from germs. Everything happens in a super clean space to keep it safe.

The machines work really fast and save energy at the same time. Some of them can fill up to 18,000 bottles in just one hour. They also run for a long time without stopping, which helps businesses save time and money.

GEA machines clean the air and their workspaces automatically to keep germs out. This means workers don’t have to clean them by hand, which makes the process safer and easier. Companies trust these machines to keep everything sterile.

GEA started as a small company trading metals but has grown to be a global leader in making machines. They’re part of important sustainability groups and are trusted all over the world for helping businesses stay clean and efficient.

SIPA S.p.A

Year Founded: 1980

Main Products

• Preform and bottle manufacturing systems
• Container production systems
• Filling systems
• Integrated blow-molding solutions
• Molds and tooling
• Palletizing systems

Company Description

SIPA is a company from Italy that makes machines to create and fill bottles. They have factories in different places, like Italy, Romania, and China. They’ve been making these machines for over 40 years and help companies all over the world.

Their machines are used for drinks, cleaning products, medicine, and more. Some machines make bottles, others fill them, and some do both at the same time. Companies like them because their machines are easy to use and work really well.

SIPA works with businesses that make food, cosmetics, and chemicals. Their machines save energy, lower costs, and work with many types of bottles. They make sure everything they build is safe for the planet and high quality.

They also help design bottles and test them in labs to make sure they’re strong and won’t break. SIPA works closely with the companies they help, teaching them and finding the best ways to get things done.

Brevetti Angela S.R.L

Year Founded: 1977

Main Products

• SYFPAC® LVP: BFS machine for Large Volume Parenterals (50ml to 2500ml)
• SYFPAC® SECUREJECT®: BFS machine for Pre-Filled Syringes (0.5ml to 20ml)
• SYFPAC® SVP: BFS machine for Small Volume Parenterals (vials and ampoules, 0.2ml to 50ml)
• SYFPAC® TWIN: Double-mould BFS machine for Small Volume Parenterals (0.2ml to 20ml)

Company Description

Brevetti Angela is a company from Italy that makes special machines for packing medicines in clean and safe ways. They use a method called Blow-Fill-Seal (BFS), which creates containers and fills them with medicine all in one step. The company started with the Consolaro family’s skills in making plastic molds and used that to help the medical world.

Their SYFPAC® machines turn tiny plastic pieces into bottles or containers in just seconds. These machines do three jobs—making the bottle, filling it with medicine, and sealing it—without any breaks in between. Everything happens in a super clean space to make sure the medicine stays safe.

Their machines save time and money for companies by working fast and using less space. They can handle different types of plastics like PP, PE, and HDPE on the same machine. Since the machines are small and mostly automated, they need fewer workers and help keep everything clean.

Besides making medicine packages, Brevetti Angela’s machines are used for other products too. They can pack things like glue, cosmetics, creams, and even drinks like milk or juice. Companies trust them to keep products clean and safe for people to use.

Conclusion

Blow-Fill-Seal machines make packing liquids, creams, and medicines faster and safer. They work with all kinds of products and keep everything super clean. These machines are always getting better and help make sure packages are safe and ready to use.