English 
Arabic 
Indonesian 
Vietnamese 
Malay 
Thai 
Korean 
Russian 
French 
Italian 
Japanese 
Portuguese 
Turkish 
Spanish 
GZB100 Pre-Filled Syringe Vacuum Filling and Stoppering Machine
The GZB100 Pre-Filled Syringe Vacuum Filling and Stoppering Machine is specially designed by our company for the aseptic and efficient filling of pre-filled syringes. This fully automatic packaging equipment operates smoothly, is easy to use, and is equipped with intelligent detection systems. It features high automation, excellent working efficiency, and simple maintenance, making it an ideal solution for syringe filling and stoppering.
GZB100 Pre-Filled Syringe Vacuum Filling and Stoppering Machine – Detailed Introduction
- This product is widely applicable toSCF (Prefilled syringe) syringes from BD, BG, SCHOTT and major domestic manufacturers. Other types of syringes can also be customized.
- The surface is made of SUS304 stainless steel, and the contact parts are made of SUS316L stainless steel and medical silicon rubber, which fully meets the requirements of GMP specifications.
- The ceramic plunger pump realizes quantitative filling, is resistant to acid and alkali corrosion, wear-resisting and high temperature, and has high filling accuracy.
- The conveying and sorting of the rubber plugs are realized by the vibratory feeder, which is made of SUS316L stainless steel clean plate with bright surface treatment and no clean dead corners.
- It adopts internationally renowned electrical components and implements interference-free modular control. Synchronous actions are all controlled by servo motors. Automatic filling and stoppering are implemented, which is accurate, reliable and easy to operate.
- The operation of the motor is controlled by the PLC programming controller. The human-computer interaction interface monitors and displays the working status of each station in real time, and automatically alarms and displays the fault location in real time, and the fault prompts.
- A variety of filling doses and filling methods are available.
- The injection needle is used for filling with the liquid level rising to prevent splashing of liquid medicine.
- The vacuum filling system is suitable for viscous materials to ensure that the liquid medicine fills the filling space without bubbles or faults, and improves the qualified rate of finished products.
- The vacuum stopper system avoids particles generated by the vibration and friction of the rubber stopper, and ensures that the rubber stopper is in close contact with the liquid surface.
- Modular design, easy to locate, easy to expand, can be used as a stand-alone machine, can also be connected to the nesting machine, rotating rod machine, labeling machine, light inspection machine and other equipment to form a production line.
- Optionalhundred-level laminar flow hood to achieve high-demand clean production.
GZB100 Pre-Filled Syringe Vacuum Filling and Stoppering Machine Details
Conveyor structure
Quantitative filling
Turntable
Vibratory bowl
Machines Product
GZB100 Pre-Filled Syringe Vacuum Filling and Stoppering Machine Specifications
| Applicable Materials | Liquid and ointment |
|---|---|
| Applicable Syringe Specifications | 0.5-10ml (Different specifications of syringes need to replace the mold) |
| Filling Range | 0.3-10ml (The filling pump needs to be replaced when the filling volume differs greatly) |
| Number of Filling Heads | 1 |
| Number of Capping Heads | 1 |
| Filling Accuracy | ≤±1% |
| Production Capacity | 600-800 p/h |
| Total Power | 2KW |
| Voltage | 380V / 220V 50/60Hz |
| Compressed Air | 0.55-0.75Mpa 15L/S |
| Dimensions | L808 × W758 × H1760mm (Without laminar flow hood) |
| Total Weight | 380KG |
GZB100 Pre-Filled Syringe Vacuum Filling and Stoppering Machine FAQ
Transparency is the cornerstone of our Yundu team. That’s why below, you can find the most common questions and answers we receive surrounding our Liquid Filling systems.
The GZB100 is an advanced pharmaceutical machine designed for vacuum filling and stoppering of pre-filled syringes. It ensures aseptic processing, high accuracy, and stable production. This machine is widely applied in the pharmaceutical, biotech, and healthcare industries, especially for injectable solutions, vaccines, and other sterile products.
The GZB100 uses vacuum technology to remove air and fill syringes precisely with liquid medication. After filling, the machine automatically inserts stoppers to seal the syringe under sterile conditions. The process minimizes bubbles, ensures accurate dosage, and guarantees product safety according to GMP standards.
The GZB100 can handle a filling range of 0.3ml to 10ml, depending on syringe specifications. For different volumes, the filling pump can be replaced to ensure consistent accuracy. This flexibility makes it suitable for various pharmaceutical applications, from vaccines to injectable drugs.
The GZB100 delivers a production capacity of 600–800 pieces per hour, ensuring efficiency for medium-scale pharmaceutical manufacturing. Its automation reduces labor costs and enhances output consistency, making it a reliable choice for pre-filled syringe production lines.
The GZB100 achieves a filling accuracy of ≤±1%, ensuring precise dosing for every syringe. This high level of accuracy is essential for injectable medications, as it maintains product integrity, patient safety, and compliance with strict pharmaceutical standards.
The GZB100 is compatible with syringe sizes from 0.5ml to 10ml. For different syringe specifications, the mold can be replaced easily. This adaptability makes the machine versatile for pharmaceutical companies producing multiple syringe types.
Yes. The GZB100 is a fully automatic aseptic filling and stoppering machine. It features intelligent detection devices, smooth operation, and user-friendly controls. With minimal manual intervention, it increases efficiency and reduces contamination risks in syringe production.
The GZB100 operates at 2KW total power, with voltage options of 380V or 220V, 50/60Hz. It requires compressed air at 0.55–0.75Mpa, 15L/S. These standard utilities make the machine compatible with most pharmaceutical factory setups.
The GZB100 measures L808 × W758 × H1760mm (without laminar flow hood) and weighs 380kg. Its compact footprint makes it suitable for cleanroom installations, while still delivering stable, high-performance syringe filling and stoppering.
The GZB100 combines precision, automation, and reliability for pre-filled syringe production. With vacuum filling, aseptic design, intelligent detection, and easy maintenance, it ensures GMP compliance and high efficiency. It is an ideal choice for pharmaceutical companies seeking accuracy and productivity.
Related Products
The nesting machine is an automatic device that takes out the prefilled syringes stored in the nest box and distributes the prefilled syringes to the filling station in an orderly manner through intelligent control. It can be used with the filling and plugging machine or the plunger rod assembling and labeling machine, which solves the problems of slow manual material distribution and easy breaking, and improves the production efficiency.
This syringe filling machine features a 304 stainless steel body, complying with GMP standards. It operates pneumatically, ideal for humid, explosion-proof environments. The drip-proof nozzle ensures accurate filling, with customizable nozzle sizes. A five-way rotary valve allows flexible material feeding. Pneumatic components are from renowned brands, ensuring stability. The control panel includes a barometer, and the filling volume is easily adjustable. The foot switch offers manual/automatic feeding modes.
The GZB200 Pre-Filled Syringe Vacuum Filling and Stoppering Machine is specially designed by our company for the production of prefilled syringes. It is an automatic packaging system for aseptic and efficient syringe filling. The machine runs smoothly, is easy to operate, and comes equipped with intelligent detection devices. Featuring a high level of automation, excellent working efficiency, and simple maintenance, it is the ideal solution for filling and stoppering prefilled syringes.
The DZA100 Pre-Filled Plastic Syringe Filling and Capping Machine offers aseptic, precise, and efficient syringe filling with smooth operation, intelligent detection, and easy maintenance. With high automation and reliable performance, it is the perfect solution for pharmaceutical syringe production.
